Quan Jiang

Quan Jiang

Adjunct Professor

Email: [email protected]

Phone: (313) 916-8735

Positions

2022-Present   Professor, Department of Radiology, Michigan State University College of Osteopathic Medicine, Lansing, Michigan

2016-Present   Professor, Department of Physics, Oakland University, Rochester Hill, Michigan

2012-Present   Professor, Department of Neurology, Wayne State University, Detroit, Michigan

2007-Present   Senior Bioscientific Staff (level 3), Department of Neurology, Henry Ford Hospital, Detroit, Michigan

2003-2011       Associate Professor, Department of Neurology, Wayne State University, Detroit, Michigan.

2000-2006       Senior Staff (Bioscientific Staff, level 1 and 2), Department of Neurology, Henry Ford Hospital, Detroit, Michigan

1991-1999       Assistant and Associate Staff, Department of Neurology, Henry Ford Hospital, Detroit, Michigan

Research Interests

My research were focused on the development of magnetic resonance imaging (MRI) methodology and image analysis for treatment planning and risk prediction of neurological diseases, which include perfusion, diffusion, spectroscopic imaging, magnetization transfer imaging, blood brain barrier permeability, mean vascular density, susceptibility weighted MRI (SWI) incorporating phase information, MRI molecular imaging, q space diffusion tensor imaging (q ball and persistent angular structure MRI), functional MRI (fMRI), and apply them to the investigation of neurological injury/diseases, such as traumatic brain injury, diabetes, stroke, multiple sclerosis etc. My current research focus is to develop MRI methodologies and analysis for quantitative evaluation of glymphatic response to neurological diseases. My MRI research at Henry Ford Hospital (HFH) has been supported by over 20 grants from the National Institutes of Health (NIH) continuously since 1999.

Recent Publications

(See My Bibliography for the full list of published work and presentations)

Hu J, Shen Y, Fahmy LM, Krishnamurthy S, Li J, Zhang L, Chen Y, Haacke EM, Jiang Q. The role of parenchymal vascular system in cerebrospinal fluid tracer clearance. European Radiology. 2022 Jul 19. doi: 10.1007/s00330-022-09022-9.

Li L, Ding G, Zhang L, Davoodi-Bojd E, Chopp M, Li Q, Zhang ZG, Jiang Q. Aging-related Alterations of Glymphatic Transport in Rat: in vivo MRI and Kinetic Study. Fronties Aging. 2022;14:841798.

Kaur J, Fahmy LM, Davoodi-Bojd E, Zhang L, Ding G, Hu J, Zhang Z, Chopp M, Jiang Q. Waste Clearance in the Brain. Fronties Aging. published: 07 July 2021; doi: 10.3389/fnana.2021.665803.

LM Fahmy, Y Chen, S Xuan, EM Haacke, J Hu, Q Jiang. All central nerval system neuro- and vascular-communication channeles are surrounded with cerevrospinal fluid. Frontiers in Neurology. 17 June, 2021. doi: 10.3389/fneur.2021.614636.

Li L, Chopp M, Ding G, Davoodi-Bojd E, Zhang L, Li Q, Zhang Y, Xiong Y, Jiang Q. MRI Detection of Impairment of Glymphatic Function in Rat after Mild Traumatic Brain Injury. Brain Research. 2020, 1747, 147062.

Kaur J, Davoodi-Bojd E, Fahmy LM, Zhang L, Ding G, Hu J, Zhang Z, Chopp M, Jiang Q. Magnetic Resonance Imaging and Modeling of the Glymphatic System. Diagnostics. 2020, 10(6):May31.

Zhou Y, Cai J, Zhang W, Gong X, Yan S, Zhang K, Luo Z, Sun J, Jiang Q, Lou M. Impairment of glymphatic pathway and putative meningeal lymphatic vessels in aging human. Ann Neurology. 2020;87:357–369.

Shen Y, Hu J, Eteer K, Chen Y, Buch S, Alhourani H, Shah K, Jiang Q, Ge Y, Haacke EM. Detecting Sub-Voxel Microvasculature with USPIO-Enhanced Susceptibility-weighted MRI at 7T. Magn Reson Imaging. 2020, 67;90-100.

Wang H, Jiang Q, Shen Y, Zhang L, Haacke EM, Ge Y, Qi S, Hu J. The Capability of Detecting Small Vessels Beyond the Conventional MRI Sensitivity Using Iron-based Contrast Agent Enhanced Susceptibility Weighted Imaging. NMR in Biomedicine. 2020, 33(5): e4256.

Zhang L, Chopp M, Jiang Q, Zhang Z: Role of the glymphatic system in ageing and diabetes mellitus impaired cognitive function. Stroke Vasc Neurol 2019, 4(2):90-92.

Jiang Q. MRI and Glymphatic System. Stroke Vasc Neurol. 2019;4(2): 75-77.

Davoodi-Bojd E, Ding G, Zhang L, Li Q, Li L, Chopp M, Zhang Z, Jiang Q: Modeling glymphatic system of the brain using MRI. Neuroimage. 2019, 188:616-627.

Ding G, Chopp M, Li L, Zhang L, Davoodi-Bojd E, Li Q, Zhang ZG, Jiang Q. MRI investigation of glymphatic responses to Gd-DTPA infusion rates. J Neurosci Res. 2018;96:1876-1886.

Kokeny P, Cheng YN, Liu S, Xie H, and Jiang Q. Quantifications of In Vivo Labeled Stem Cells Based on Measurements of Magnetic Moments. Magn Reson Imaging, 2017;35:141-147.

Nejad-Davarani SP, Bagher-Ebadian H, Ewing, J, Noll DC, Chopp, M, Jiang Q. A Parametric Model of the Brain Vascular System for Estimation of the Arterial Input Function (AIF) at the Tissue Level. NMR in Biomedicine. 2017, 30:5, e3695.

Nejad-Davarani SP, Bagher-Ebadian H, Ewing, J, Noll DC, Chopp, M, Jiang Q. An Extended Vascular Model for Less Biased Estimation of Permeability Parameters in DCE-T1 Images. NMR in Biomedicine. 2017; 30:6, e3698.

Jiang Q, Zhang L, Ding GL, Davoodi-Bojd E, Li QJ, Li L, Sadry N, Nedergaard M, Chopp M, and Zhang ZG. Impairment of the Glymphatic System after Diabetes. J Cereb Blood Flow Metab. 2017;37:1326-37.