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Eye Research Institute

Dodge Hall
118 Library Drive
Rochester, Michigan 48309-4479
(location map)

Eye Research Institute

Dodge Hall
118 Library Drive
Rochester, Michigan 48309-4479
(location map)

two women wearing white coats, using equipment in a lab

Facilities

The ERI contains multiple research facilities in its efforts to research the underlying causes and possible cures of many eye diseases. These facilities are available to ERI faculty, staff and student researchers.

Cell and Molecular Biology Support Module

The module provides central facilities and expertise for cell and tissue culture, cryopreservation of cell lines, mycoplasma test monitoring of cell lines, DNA sequencing, guidance for PCR design and DNA construct design, real time PCR for genotyping and gene expression assays (Sybr-green and Taqman chemistries, mouse and human), as well as basic training and use of Bioinformatics tools (stand alone and web based). Management of ChIP-on-Chip (Chromatin Immunoprecipitation on DNA Chip array) project design and delivery is also possible to explore RNA-Polymerase-II binding, Transcription Factor binding, and Epigenomic regulation of human and mouse genes. (26,000 genes)

Equipment
  • Tissue culture hoods are available for BioSafety Level -2 work (BSL-2).
  • A wide screen Unix (Mac OS-X Server) work station is available for molecular biology and bioinformatics projects with multiple protected accounts for many labs and users.
  • Locations of Mol & Cell Biology services and equipment:
  • Rm 427 (Tissue Culture, Water purification)
  • Rm 429 (Ultracentrifuge, bench Autoclave, Vacu-fuge, Mastercycler gradient, Biospec, UV-Stratalinker)
  • Rm 430 (Real time PCR, Automated DNA sequencing)
  • Rm 431 (Molecular workstation, student computer access, work room, MacVector, Osprey Software.)
  • Rm 414 (in situ hybridization, immunochemistry)
User Access and Biosafety Compliance
All users of any part of the module must obtain, read, and sign for a copy of the Module's Standard Operating Procedures for Biosafety. A copy may be obtained from Dr. Kenneth Mitton, and is on the desk just inside Room 427.

Dr. Kenneth Mitton
Associate Professor of Biomedical Sciences, and
Director Cell and Molecular Biology support module
412 Dodge Hall of Engineering
(248) 370-2079
mitton@oakland.edu
Pediatric Retinal Research Laboratory

The ERI launched the Virginia and Clarence Clohset Pediatric Retinal Research Laboratory (PRRL) in 2011, which is believed to be the only laboratory in the country devoted solely to pediatric retinal research.

The renovated lab in Dodge Hall is under the leadership of Dr. Michael Trese of the Beaumont Hospitals, who is a clinical professor of biomedical sciences with the institute. Additional ERI faculty members working with the laboratory include Dr. Kimberly Drenser and Dr. Anthony Capone.

Approximately $480,000 in funding for the laboratory was donated by the Retinopathy of Prematurity and Related Diseases (ROPARD) Foundation, which is striving to eliminate blindness and low vision in children from premature birth and retinal disease. ROPARD made its contribution through support from two donor families — the Clohsets and the Bergquist families — along with a number of individual donors.